Critical analytics for manufacturing personalized medicine
Critical Analytics for Manufacturing Personalized-Medicine, or CAMP, is an Interdisciplinary Research Group in Singapore and at MIT focusing on better ways to produce living cells as medicine delivered to humans. CAMP launched in June 2019, with the goal to address two key bottlenecks facing production of a range of potential cell therapies: critical quality attributes (CQA) and process analytic technologies (PAT) for cell therapy production.
CAMP invents and demonstrate these CQA/PAT capabilities, from stem to immune cells, addressing ailments ranging from cancer to tissue degeneration, targeting adherent and suspended cells, with and without genetic engineering, and leveraging deep and growing collaborations in Singapore and at MIT. Our goal is that this applied research and the new workforce that develops with and for the manufacturing industry & clinics will provide more patients with access to promising, approved therapies.
The Singapore National Research Foundation supports this multi-million, multi-year project convening MIT and Singapore investigators and talented researchers from engineering, science, and clinical backgrounds.
Current projects
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| Label-free critical quality attributes for personalized efficacy of cell therapies, including multivariate analysis of biological and biophysical attributes | Rapid critical quality attributes for safety of cell sources and cell therapy products, informing process analytic technologies and speeding product release | Process analytic technologies for cell proliferation and recovery , including inline and intermittent monitoring to promote efficacy and safety attributes for timely cell product release |